Changes have been made that affect the global template, Normal.dotm.....

Background: Office 2007 on Windows 7 64bit 

The message pops up at the exit of Word applicaiton 2007,

Workaround:

1. Make sure no WinWord.exe is running
2. Go to C:\Users\%username%\AppData\Roaming\Microsoft\Templates, and back up and remove everything in that folder